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p16 Immunohistochemical Expression in Nephrogenic Adenoma

Nephrogenic adenoma (NA) is a rare metaplastic entity commonly associated with a prior urothelial injury. Most are seen in the urinary bladder and a minority involve the urethra. In this study, we evaluated the expression of p16 as a surrogate marker of this entity and correlated it with clinical pa...

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Autores principales: Alvarez Moreno, Juan Carlos, Ghani, Hafiz A, Ovechko, Vasily, Clement, Cecilia, Eyzaguirre, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393285/
https://www.ncbi.nlm.nih.gov/pubmed/37533615
http://dx.doi.org/10.7759/cureus.41285
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author Alvarez Moreno, Juan Carlos
Ghani, Hafiz A
Ovechko, Vasily
Clement, Cecilia
Eyzaguirre, Eduardo
author_facet Alvarez Moreno, Juan Carlos
Ghani, Hafiz A
Ovechko, Vasily
Clement, Cecilia
Eyzaguirre, Eduardo
author_sort Alvarez Moreno, Juan Carlos
collection PubMed
description Nephrogenic adenoma (NA) is a rare metaplastic entity commonly associated with a prior urothelial injury. Most are seen in the urinary bladder and a minority involve the urethra. In this study, we evaluated the expression of p16 as a surrogate marker of this entity and correlated it with clinical pathological parameters. A total of 17 cases of NA were retrospectively studied to assess the immunohistochemical expression of p16 and its value for the diagnosis of this entity.
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spelling pubmed-103932852023-08-02 p16 Immunohistochemical Expression in Nephrogenic Adenoma Alvarez Moreno, Juan Carlos Ghani, Hafiz A Ovechko, Vasily Clement, Cecilia Eyzaguirre, Eduardo Cureus Pathology Nephrogenic adenoma (NA) is a rare metaplastic entity commonly associated with a prior urothelial injury. Most are seen in the urinary bladder and a minority involve the urethra. In this study, we evaluated the expression of p16 as a surrogate marker of this entity and correlated it with clinical pathological parameters. A total of 17 cases of NA were retrospectively studied to assess the immunohistochemical expression of p16 and its value for the diagnosis of this entity. Cureus 2023-07-02 /pmc/articles/PMC10393285/ /pubmed/37533615 http://dx.doi.org/10.7759/cureus.41285 Text en Copyright © 2023, Alvarez Moreno et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Alvarez Moreno, Juan Carlos
Ghani, Hafiz A
Ovechko, Vasily
Clement, Cecilia
Eyzaguirre, Eduardo
p16 Immunohistochemical Expression in Nephrogenic Adenoma
title p16 Immunohistochemical Expression in Nephrogenic Adenoma
title_full p16 Immunohistochemical Expression in Nephrogenic Adenoma
title_fullStr p16 Immunohistochemical Expression in Nephrogenic Adenoma
title_full_unstemmed p16 Immunohistochemical Expression in Nephrogenic Adenoma
title_short p16 Immunohistochemical Expression in Nephrogenic Adenoma
title_sort p16 immunohistochemical expression in nephrogenic adenoma
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393285/
https://www.ncbi.nlm.nih.gov/pubmed/37533615
http://dx.doi.org/10.7759/cureus.41285
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