Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt–Hopkins syndrome

Pitt–Hopkins syndrome is an autism spectrum disorder caused by autosomal dominant mutations in the human transcription factor 4 gene (TCF4). One pathobiological process caused by murine Tcf4 mutation is a cell autonomous reduction in oligodendrocytes and myelination. In this study, we show that the...

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Detalles Bibliográficos
Autores principales: Bohlen, Joseph F, Cleary, Colin M, Das, Debamitra, Sripathy, Srinidhi Rao, Sadowski, Norah, Shim, Gina, Kenney, Rakaia F, Buchler, Ingrid P, Banerji, Tapasree, Scanlan, Thomas S, Mulkey, Daniel K, Maher, Brady J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393406/
https://www.ncbi.nlm.nih.gov/pubmed/37068912
http://dx.doi.org/10.1093/brain/awad057

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