Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization

Vascular endothelial polarity induced by blood flow plays crucial roles in the development of atherosclerosis. Loss of endothelial polarity leads to an increase in permeability and leukocyte recruitment, which are crucial hallmarks of atherosclerotic initiation. Endothelial cells exhibit a morpholog...

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Detalles Bibliográficos
Autores principales: Qu, Kai, Wang, Caihong, Huang, Lu, Qin, Xian, Zhang, Kun, Qiu, Juhui, Wang, Guixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393427/
https://www.ncbi.nlm.nih.gov/pubmed/37533755
http://dx.doi.org/10.1063/5.0141289

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