Serum IFNα2 levels are associated with disease activity and outperform IFN-I gene signature in a longitudinal childhood-onset SLE cohort

OBJECTIVE: To study the association of serum IFNα2 levels measured by ultrasensitive single-molecule array (Simoa) and the IFN-I gene signature (IGS) with disease activity and determine whether these assays can mark disease activity states in a longitudinal cohort of childhood-onset SLE (cSLE) patie...

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Detalles Bibliográficos
Autores principales: Wahadat, M Javad, Qi, Hongchao, van Helden-Meeuwsen, Cornelia G, Huijser, Erika, van den Berg, Lotte, van Dijk-Hummelman, Annette, Göpfert, Jens C, Heine, Anne, Verkaaik, Marleen, Schreurs, Marco W J, Dik, Willem A, Kamphuis, Sylvia, Versnel, Marjan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393436/
https://www.ncbi.nlm.nih.gov/pubmed/36515466
http://dx.doi.org/10.1093/rheumatology/keac698

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