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Mitochondrial DNA: a novel indicator of active inflammation in ANCA-associated vasculitides

OBJECTIVES: ANCA-associated vasculitis (AAV) includes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). ANCA triggers neutrophil extracellular trap formation, which releases either mitochondrial (mt) DNA or nuclear DNA (n) DNA, contributing to inflammation. Our aim was to pr...

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Detalles Bibliográficos
Autores principales:	Giaglis, Stavros, Daoudlarian, Douglas, Thiel, Jens, Rizzi, Marta, Kyburz, Diego, Venhoff, Nils, Walker, Ulrich A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393440/ https://www.ncbi.nlm.nih.gov/pubmed/36645235 http://dx.doi.org/10.1093/rheumatology/kead015

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