Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths in the United States. Tyrosine sulfation, catalyzed by the tyrosylprotein sulfotransferase 2 (TPST2), is a post-translational modification essential for protein–protein interactions and cellul...

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Detalles Bibliográficos
Autores principales: Cai, Xinran, Li, Sihan, Zeng, Xuemei, Xu, Meishu, Wang, Zehua, Singhi, Aatur D., Tang, Daolin, Li, Song, Yates, Nathan A., Yang, Da, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393550/
https://www.ncbi.nlm.nih.gov/pubmed/37192689
http://dx.doi.org/10.1016/j.jcmgh.2023.05.003

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