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Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report

Invasive candidiasis is rare but is associated with high mortality in immunocompromised or critically ill patients. Here, we present a case of a 55-year-old man with untreated diabetes who was diagnosed with coronavirus disease 2019 and subsequently developed invasive candidiasis. The patient presen...

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Autores principales: Ijiri, Atsuhiro, Terayama, Takero, Sugiura, Hiroaki, Kaneko, Mayuko, Seno, Soichiro, Kiriu, Nobuaki, Kato, Hiroshi, Sekine, Yasumasa, Shinmoto, Hiroshi, Kiyozumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393609/
https://www.ncbi.nlm.nih.gov/pubmed/37539445
http://dx.doi.org/10.1016/j.radcr.2023.07.017
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author Ijiri, Atsuhiro
Terayama, Takero
Sugiura, Hiroaki
Kaneko, Mayuko
Seno, Soichiro
Kiriu, Nobuaki
Kato, Hiroshi
Sekine, Yasumasa
Shinmoto, Hiroshi
Kiyozumi, Tetsuro
author_facet Ijiri, Atsuhiro
Terayama, Takero
Sugiura, Hiroaki
Kaneko, Mayuko
Seno, Soichiro
Kiriu, Nobuaki
Kato, Hiroshi
Sekine, Yasumasa
Shinmoto, Hiroshi
Kiyozumi, Tetsuro
author_sort Ijiri, Atsuhiro
collection PubMed
description Invasive candidiasis is rare but is associated with high mortality in immunocompromised or critically ill patients. Here, we present a case of a 55-year-old man with untreated diabetes who was diagnosed with coronavirus disease 2019 and subsequently developed invasive candidiasis. The patient presented with fever, tachycardia, and tachypnea. Chest computed tomography revealed multiple consolidations mainly distributed around the bronchovascular bundles with bronchiectatic cavity formation, which initially raised suspicion for invasive pulmonary aspergillosis. However, subsequent testing confirmed Candida albicans infection; hence, we changed the antifungal agents effective for invasive candidiasis. This improved the patient's respiratory status, and he was then successfully weaned from mechanical ventilation. This case report highlights the importance of considering invasive candidiasis in the differential diagnosis of patients with bronchiectatic cavities on chest computed tomography, particularly in immunocompromised or critically ill patients with risk factors for invasive candidiasis.
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spelling pubmed-103936092023-08-03 Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report Ijiri, Atsuhiro Terayama, Takero Sugiura, Hiroaki Kaneko, Mayuko Seno, Soichiro Kiriu, Nobuaki Kato, Hiroshi Sekine, Yasumasa Shinmoto, Hiroshi Kiyozumi, Tetsuro Radiol Case Rep Case Report Invasive candidiasis is rare but is associated with high mortality in immunocompromised or critically ill patients. Here, we present a case of a 55-year-old man with untreated diabetes who was diagnosed with coronavirus disease 2019 and subsequently developed invasive candidiasis. The patient presented with fever, tachycardia, and tachypnea. Chest computed tomography revealed multiple consolidations mainly distributed around the bronchovascular bundles with bronchiectatic cavity formation, which initially raised suspicion for invasive pulmonary aspergillosis. However, subsequent testing confirmed Candida albicans infection; hence, we changed the antifungal agents effective for invasive candidiasis. This improved the patient's respiratory status, and he was then successfully weaned from mechanical ventilation. This case report highlights the importance of considering invasive candidiasis in the differential diagnosis of patients with bronchiectatic cavities on chest computed tomography, particularly in immunocompromised or critically ill patients with risk factors for invasive candidiasis. Elsevier 2023-07-25 /pmc/articles/PMC10393609/ /pubmed/37539445 http://dx.doi.org/10.1016/j.radcr.2023.07.017 Text en © 2023 Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ijiri, Atsuhiro
Terayama, Takero
Sugiura, Hiroaki
Kaneko, Mayuko
Seno, Soichiro
Kiriu, Nobuaki
Kato, Hiroshi
Sekine, Yasumasa
Shinmoto, Hiroshi
Kiyozumi, Tetsuro
Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title_full Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title_fullStr Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title_full_unstemmed Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title_short Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report
title_sort invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393609/
https://www.ncbi.nlm.nih.gov/pubmed/37539445
http://dx.doi.org/10.1016/j.radcr.2023.07.017
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