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Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review

Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST)...

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Detalles Bibliográficos
Autores principales: Peng, Yi-Fan, Wang, Lin-Lin, Gu, Juan-Hua, Zeng, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393630/
https://www.ncbi.nlm.nih.gov/pubmed/37539097
http://dx.doi.org/10.1016/j.heliyon.2023.e18288
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author Peng, Yi-Fan
Wang, Lin-Lin
Gu, Juan-Hua
Zeng, Yue-Qin
author_facet Peng, Yi-Fan
Wang, Lin-Lin
Gu, Juan-Hua
Zeng, Yue-Qin
author_sort Peng, Yi-Fan
collection PubMed
description Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST), a carotenoid primarily derived from algae and aquatic animals, possesses multiple pharmacological properties such as anti-inflammatory, anti-apoptotic, and antioxidant stress effects. Prior research suggests that AST may have antidepressant properties. This mini-review highlights the potential mechanisms by which AST can prevent depression, providing novel insights into drug research for depression treatment. Specifically, this mechanism suggests that astaxanthin may improve sleep and thus potentially aid in the treatment of depression.
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spelling pubmed-103936302023-08-03 Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review Peng, Yi-Fan Wang, Lin-Lin Gu, Juan-Hua Zeng, Yue-Qin Heliyon Review Article Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST), a carotenoid primarily derived from algae and aquatic animals, possesses multiple pharmacological properties such as anti-inflammatory, anti-apoptotic, and antioxidant stress effects. Prior research suggests that AST may have antidepressant properties. This mini-review highlights the potential mechanisms by which AST can prevent depression, providing novel insights into drug research for depression treatment. Specifically, this mechanism suggests that astaxanthin may improve sleep and thus potentially aid in the treatment of depression. Elsevier 2023-07-17 /pmc/articles/PMC10393630/ /pubmed/37539097 http://dx.doi.org/10.1016/j.heliyon.2023.e18288 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Peng, Yi-Fan
Wang, Lin-Lin
Gu, Juan-Hua
Zeng, Yue-Qin
Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_full Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_fullStr Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_full_unstemmed Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_short Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_sort effects of astaxanthin on depressive and sleep symptoms: a narrative mini-review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393630/
https://www.ncbi.nlm.nih.gov/pubmed/37539097
http://dx.doi.org/10.1016/j.heliyon.2023.e18288
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