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Inhibition of microRNA-122 alleviates pyroptosis by targeting dual-specificity phosphatase 4 in myocardial ischemia/reperfusion injury

Pyroptosis is a type of programmed cell death that induces myocardial ischemia-reperfusion injury (I/RI), which leads to cardiac dysfunction and even lethal reperfusion injury. MiR-122 is a liver-specific miRNA associated with coronary heart disease, but its role in pyroptosis activation in myocardi...

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Detalles Bibliográficos
Autores principales: Wu, Hongjin, Fu, Qiang, Li, Zhong, Wei, Huamin, Qin, Shuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393637/
https://www.ncbi.nlm.nih.gov/pubmed/37539226
http://dx.doi.org/10.1016/j.heliyon.2023.e18238