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Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease

Paneth cells (PC) play a key role in the innate immune response of intestine epithelium, and PC defects contribute to the pathogenesis of Crohn’s disease (CD). In this study, we utilized active CD tissues and advanced oxidation protein products (AOPP)-challenged C57BL/6 mouse model to investigate th...

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Detalles Bibliográficos
Autores principales:	Shi, Jie, Wang, Weidong, Sun, Shibo, Xu, Xiaoping, Fei, Jieying, Zhou, Qian, Qin, Caolitao, Ou, Shiyu, Wu, Fengfei, Wu, Fang ting, Xu, Tianyan, Bai, Lan, Xie, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393771/ https://www.ncbi.nlm.nih.gov/pubmed/37539032 http://dx.doi.org/10.1016/j.isci.2023.107312

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