Mitochondrial UQCC3 controls embryonic and tumor angiogenesis by regulating VEGF expression

Mitochondria play important roles in angiogenesis. However, the mechanisms remain elusive. In this study, we found that mitochondrial ubiquinol-cytochrome c reductase complex assembly factor 3 (UQCC3) is a key regulator of angiogenesis. TALEN-mediated knockout of Uqcc3 in mice caused embryonic letha...

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Detalles Bibliográficos
Autores principales: Zhang, Guimin, Liu, Binrui, Yang, Yun, Xie, Shuo, Chen, Lingcheng, Luo, Hui, Zhong, Jian, Wei, Yinhao, Guo, Fengzhu, Gan, Jia, Zhu, Fan, Xu, Lin, Li, Qiqi, Shen, Yuge, Zhang, Huajin, Liu, Yan, Li, Rong, Deng, Hongxin, Yang, Hanshuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393800/
https://www.ncbi.nlm.nih.gov/pubmed/37539028
http://dx.doi.org/10.1016/j.isci.2023.107370

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