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Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity

Although aging is associated with progressive adiposity and a decline in liver function, the underlying molecular mechanisms and metabolic interplay are incompletely understood. Here, we demonstrate that aging induces hepatic protein kinase Cbeta (PKCβ) expression, while hepatocyte PKCβ deficiency (...

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Detalles Bibliográficos
Autores principales:	Shu, Yaoling, Gumma, Nikhil, Hassan, Faizule, Branch, Daniel A., Baer, Lisa A., Ostrowski, Michael C., Stanford, Kristin I., Baskin, Kedryn K., Mehta, Kamal D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393818/ https://www.ncbi.nlm.nih.gov/pubmed/37315788 http://dx.doi.org/10.1016/j.jbc.2023.104917

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