Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin

BACKGROUND: Antibiotic use is associated with collateral damage to the healthy microbiota. Afabicin is a first-in-class prodrug inhibitor of the FabI enzyme that, when converted to the pharmacologically active agent afabicin desphosphono, demonstrates a staphylococcal-specific spectrum of activity....

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Detalles Bibliográficos
Autores principales: Nowakowska, J, Cameron, D R, De Martino, A, Kühn, J, Le Fresne-Languille, S, Leuillet, S, Amouzou, Y, Wittke, F, Carton, T, Le Vacon, F, Chaves, R L, Nicolas-Metral, V, Vuagniaux, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393889/
https://www.ncbi.nlm.nih.gov/pubmed/37294305
http://dx.doi.org/10.1093/jac/dkad181

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