Arginine 65 methylation of Neurogenin 3 by PRMT1 is required for pancreatic endocrine development of hESCs

Neurogenin 3 (NGN3) is a key transcription factor in the cell fate determination of endocrine progenitors (EPs) in the developing pancreas. Previous studies have shown that the stability and activity of NGN3 are regulated by phosphorylation. However, the role of NGN3 methylation is poorly understood...

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Detalles Bibliográficos
Autores principales: Cho, Gahyang, Hyun, Kwangbeom, Choi, Jieun, Shin, Eunji, Kim, Bumsoo, Kim, Hail, Kim, Jaehoon, Han, Yong-Mahn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393949/
https://www.ncbi.nlm.nih.gov/pubmed/37394590
http://dx.doi.org/10.1038/s12276-023-01035-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393949/
https://www.ncbi.nlm.nih.gov/pubmed/37394590
http://dx.doi.org/10.1038/s12276-023-01035-8

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