Cargando…
CD38/ADP-ribose/TRPM2-mediated nuclear Ca(2+) signaling is essential for hepatic gluconeogenesis in fasting and diabetes
Hepatic glucose production by glucagon is crucial for glucose homeostasis during fasting, yet the underlying mechanisms remain incompletely delineated. Although CD38 has been detected in the nucleus, its function in this compartment is unknown. Here, we demonstrate that nuclear CD38 (nCD38) controls...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393965/ https://www.ncbi.nlm.nih.gov/pubmed/37394593 http://dx.doi.org/10.1038/s12276-023-01034-9 |