Mitochonic acid 5 attenuates age-related neuromuscular dysfunction associated with mitochondrial Ca(2+) overload in Caenorhabditis elegans

Mitochonic acid-5 ameliorates the pathophysiology of human mitochondrial-disease fibroblasts and Caenorhabditis elegans Duchenne muscular dystrophy and Parkinson’s disease models. Here, we found that 10 μM MA-5 attenuates the age-related decline in motor performance, loss of muscle mitochondria, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, XinTong, Seida, Miku, Abe, Takaaki, Higashitani, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394014/
https://www.ncbi.nlm.nih.gov/pubmed/37528117
http://dx.doi.org/10.1038/s41514-023-00116-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394014/
https://www.ncbi.nlm.nih.gov/pubmed/37528117
http://dx.doi.org/10.1038/s41514-023-00116-2

Ejemplares similares