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Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid

INTRODUCTION: Non-invasive diffusion-weighted imaging (DWI) to assess brain microstructural changes via cortical mean diffusivity (cMD) has been shown to be cross-sectionally associated with tau in cognitively normal older adults, suggesting that it might be an early marker of neuronal injury. Here,...

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Detalles Bibliográficos
Autores principales: Gagliardi, Geoffroy, Rodriguez-Vieitez, Elena, Montal, Victor, Sepulcre, Jorge, Diez, Ibai, Lois, Cristina, Hanseeuw, Bernard, Schultz, Aaron P., Properzi, Michael J., Papp, Kathryn V., Marshall, Gad A., Fortea, Juan, Johnson, Keith A., Sperling, Reisa A., Vannini, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394044/
https://www.ncbi.nlm.nih.gov/pubmed/37528163
http://dx.doi.org/10.1038/s43856-023-00324-7