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Acute myeloid leukemia (AML)‐derived mesenchymal stem cells induce chemoresistance and epithelial–mesenchymal transition‐like program in AML through IL‐6/JAK2/STAT3 signaling

Acute myeloid leukemia (AML) has a high rate of treatment failure due to increased prevalence of therapy resistance. Mesenchymal stem cells (MSCs) in the leukemia microenvironment contribute to chemoresistance in AML, but the specific mechanism remains unclear. The critical role of the epithelial–me...

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Detalles Bibliográficos
Autores principales:	Lu, Jianle, Dong, Qiaomei, Zhang, Shuling, Feng, Youfan, Yang, Jincai, Zhao, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394133/ https://www.ncbi.nlm.nih.gov/pubmed/37272257 http://dx.doi.org/10.1111/cas.15855

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