Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia

We systematically investigate functional and molecular measures of stemness in patients with acute myeloid leukemia (AML) using a cohort of 121 individuals. We confirm that the presence of leukemic stem cells (LSCs) detected through in vivo xenograft transplantation is associated with poor survival....

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Detalles Bibliográficos
Autores principales: Boyd, Allison L., Lu, Justin, Hollands, Cameron G., Alsostovar, Lili, Murali, Shiva, Reid, Jennifer C., Ye, Wendy, Vandersluis, Sean, Johnson, Paige, ElRafie, Amro, Porras, Deanna P., Xenocostas, Dimetri, Leber, Andrew, Leber, Brian, Foley, Ronan, Trus, Michael, Berg, Tobias, Kawata, Eri, Xenocostas, Anargyros, Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394166/
https://www.ncbi.nlm.nih.gov/pubmed/37433297
http://dx.doi.org/10.1016/j.xcrm.2023.101108

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