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Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage

BACKGROUND & AIMS: The colonic epithelium requires continuous renewal by crypt resident intestinal stem cells (ISCs) and transit-amplifying (TA) cells to maintain barrier integrity, especially after inflammatory damage. The diet of high-income countries contains increasing amounts of sugar, such...

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Detalles Bibliográficos
Autores principales:	Burr, Ansen H.P., Ji, Junyi, Ozler, Kadir, Mentrup, Heather L., Eskiocak, Onur, Yueh, Brian, Cumberland, Rachel, Menk, Ashley V., Rittenhouse, Natalie, Marshall, Chris W., Chiaranunt, Pailin, Zhang, Xiaoyi, Mullinax, Lauren, Overacre-Delgoffe, Abigail, Cooper, Vaughn S., Poholek, Amanda C., Delgoffe, Greg M., Mollen, Kevin P., Beyaz, Semir, Hand, Timothy W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394273/ https://www.ncbi.nlm.nih.gov/pubmed/37172822 http://dx.doi.org/10.1016/j.jcmgh.2023.05.001

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