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Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection

Acute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slu...

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Autores principales: Sharma, Shweta, Prakash, Prithivi R., Narayan, Ananthu, Garg, Ajay, Wig, Naveet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394442/
https://www.ncbi.nlm.nih.gov/pubmed/37538439
http://dx.doi.org/10.4103/aian.aian_61_23
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author Sharma, Shweta
Prakash, Prithivi R.
Narayan, Ananthu
Garg, Ajay
Wig, Naveet
author_facet Sharma, Shweta
Prakash, Prithivi R.
Narayan, Ananthu
Garg, Ajay
Wig, Naveet
author_sort Sharma, Shweta
collection PubMed
description Acute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slurring of speech with dysdiadochokinesia, incoordination of voluntary movements, pendular knee jerk, and intentional tremors. He had worsening transaminitis and rising bilirubin during his hospital course and was subsequently found to be hepatitis A virus (HAV) immunoglobulin-M antibody positive. Thus, we report a case of ACA with HAV infection who developed jaundice after three weeks of onset of ataxia, a rarity that has not been reported so far in medical literature.
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spelling pubmed-103944422023-08-03 Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection Sharma, Shweta Prakash, Prithivi R. Narayan, Ananthu Garg, Ajay Wig, Naveet Ann Indian Acad Neurol Case Report Acute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slurring of speech with dysdiadochokinesia, incoordination of voluntary movements, pendular knee jerk, and intentional tremors. He had worsening transaminitis and rising bilirubin during his hospital course and was subsequently found to be hepatitis A virus (HAV) immunoglobulin-M antibody positive. Thus, we report a case of ACA with HAV infection who developed jaundice after three weeks of onset of ataxia, a rarity that has not been reported so far in medical literature. Wolters Kluwer - Medknow 2023 2023-04-20 /pmc/articles/PMC10394442/ /pubmed/37538439 http://dx.doi.org/10.4103/aian.aian_61_23 Text en Copyright: © 2023 Annals of Indian Academy of Neurology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sharma, Shweta
Prakash, Prithivi R.
Narayan, Ananthu
Garg, Ajay
Wig, Naveet
Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title_full Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title_fullStr Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title_full_unstemmed Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title_short Acute Cerebellar Ataxia: A Rare Association of Hepatitis a Infection
title_sort acute cerebellar ataxia: a rare association of hepatitis a infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394442/
https://www.ncbi.nlm.nih.gov/pubmed/37538439
http://dx.doi.org/10.4103/aian.aian_61_23
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