Regulation of megakaryo/thrombopoiesis by endosomal toll-like receptor 7 and 8 activation of CD34(+) cells in a viral infection model

BACKGROUND: CD34(+) cells, megakaryocytes (MKs), and platelets express toll-like receptors (TLRs) that enable these cells to amplify the host innate immune response. However, the role of TLR7/TLR8 activation in megakaryopoiesis has not yet been investigated. OBJECTIVES: We evaluated the effect of co...

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Detalles Bibliográficos
Autores principales: Rodríguez, Camila Sofía, Charó, Nancy, Tatti, Silvio, Gómez, Ricardo Martín, D’Atri, Lina Paola, Schattner, Mirta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394566/
https://www.ncbi.nlm.nih.gov/pubmed/37538496
http://dx.doi.org/10.1016/j.rpth.2023.100184

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