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Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris

Candida auris has emerged as a global health problem with a dramatic spread by nosocomial transmission and a high mortality rate. Antifungal therapy for C. auris infections is currently limited due to widespread resistance to fluconazole and amphotericin B and increasing resistance to the front-line...

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Detalles Bibliográficos
Autores principales: Kirkman, Tim, Sketcher, Alice, de Morais Barroso, Vinicius, Ishida, Kelly, Tosin, Manuela, Dias, Marcio Vinicius Bertacine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394672/
https://www.ncbi.nlm.nih.gov/pubmed/37428844
http://dx.doi.org/10.1107/S2059798323004709