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Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris
Candida auris has emerged as a global health problem with a dramatic spread by nosocomial transmission and a high mortality rate. Antifungal therapy for C. auris infections is currently limited due to widespread resistance to fluconazole and amphotericin B and increasing resistance to the front-line...
Autores principales: | Kirkman, Tim, Sketcher, Alice, de Morais Barroso, Vinicius, Ishida, Kelly, Tosin, Manuela, Dias, Marcio Vinicius Bertacine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394672/ https://www.ncbi.nlm.nih.gov/pubmed/37428844 http://dx.doi.org/10.1107/S2059798323004709 |
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