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Sample size estimation in clinical trials using ventilator-free days as the primary outcome: a systematic review

BACKGROUND: Ventilator-free days (VFDs) are a composite endpoint increasingly used as the primary outcome in critical care trials. However, because of the skewed distribution and competitive risk between components, sample size estimation remains challenging. This systematic review was conducted to...

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Detalles Bibliográficos
Autores principales:	Renard Triché, Laurent, Futier, Emmanuel, De Carvalho, Manuela, Piñol-Domenech, Nathalie, Bodet-Contentin, Laëtitia, Jabaudon, Matthieu, Pereira, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394791/ https://www.ncbi.nlm.nih.gov/pubmed/37528425 http://dx.doi.org/10.1186/s13054-023-04562-y

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