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Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis

BACKGROUND: Excess polymorphonuclear neutrophil (PMN) recruitment or excessive neutrophil extracellular trap (NET) formation can lead to the development of multiple organ dysfunction during sepsis. M2 macrophage-derived exosomes (M2-Exos) have exhibited anti-inflammatory activities in some inflammat...

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Detalles Bibliográficos
Autores principales:	Jiao, Yang, Zhang, Ti, Liu, Mei, Zhou, Luyang, Qi, Mengzhi, Xie, Xin, Shi, Xueyin, Gu, Xiaoping, Ma, Zhengliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394797/ https://www.ncbi.nlm.nih.gov/pubmed/37533081 http://dx.doi.org/10.1186/s12929-023-00957-9

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