Cargando…

Methyltransferase-like proteins in cancer biology and potential therapeutic targeting

RNA modification has recently become a significant process of gene regulation, and the methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification, methylating various types of RNAs, including mRNA, tRNA, microRNA, rRNA, and mitochondrial RNAs. METTL proteins consist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Ya-Nan, Liu, Zhu, Hong, Lian-Lian, Li, Pei, Ling, Zhi-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394802/ https://www.ncbi.nlm.nih.gov/pubmed/37533128 http://dx.doi.org/10.1186/s13045-023-01477-7

Ejemplares similares

Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential
por: Zhu, Tian-Yu, et al.
Publicado: (2023)

Correction: Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential
por: Zhu, Tian-Yu, et al.
Publicado: (2023)

A Potential Oncogenic Role for PFKFB3 Overexpression in Gastric Cancer Progression
por: Lei, Lan, et al.
Publicado: (2021)

Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics
por: Copeland, R A, et al.
Publicado: (2013)

Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies
por: Sauter, Camille, et al.
Publicado: (2022)

Potential role of intratumor bacteria outside the gastrointestinal tract: More than passengers
por: Liu, Zhu, et al.
Publicado: (2023)

Nicotinamide N-Methyltransferase: A Promising Biomarker and Target for Human Cancer Therapy
por: Li, Xiao-Yu, et al.
Publicado: (2022)

Golgi scaffold protein PAQR3 as a candidate suppressor of gastric cardia adenocarcinoma via regulating TGF‐β/Smad pathway
por: Wu, Ying‐Li, et al.
Publicado: (2022)

Circulating methylated THBS1 DNAs as a novel marker for predicting peritoneal dissemination in gastric cancer
por: Hu, Xuan‐Yu, et al.
Publicado: (2021)

The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck
por: Saloura, Vassiliki, et al.
Publicado: (2018)

Methyltransferase like 7B is a potential therapeutic target for reversing EGFR-TKIs resistance in lung adenocarcinoma
por: Song, Huibin, et al.
Publicado: (2022)

Protein Kinase CK2, a Potential Therapeutic Target in Carcinoma Management
por: Lian, Haiwei, et al.
Publicado: (2019)

Characterization of the Golgi scaffold protein PAQR3, and its role in tumor suppression and metabolic pathway compartmentalization
por: Lei, Lan, et al.
Publicado: (2020)

Histone Methyltransferase EZH2: A Potential Therapeutic Target for Kidney Diseases
por: Li, Tingting, et al.
Publicado: (2021)

Histone Methyltransferases as Therapeutic Targets for Kidney Diseases
por: Yu, Chao, et al.
Publicado: (2019)

Protein Arginine Methyltransferase 5 as a Therapeutic Target for KRAS Mutated Colorectal Cancer
por: Shifteh, David, et al.
Publicado: (2020)

Molecular Identification of Carnosine N-Methyltransferase as Chicken Histamine N-Methyltransferase-Like Protein (HNMT-Like)
por: Drozak, Jakub, et al.
Publicado: (2013)

Structural biology and chemistry of protein arginine methyltransferases
por: Schapira, Matthieu, et al.
Publicado: (2014)

Chemical Biology of Protein N‐Terminal Methyltransferases
por: Huang, Rong
Publicado: (2019)

DNA Methyltransferases in Cancer: Biology, Paradox, Aberrations, and Targeted Therapy
por: Zhang, Jiayu, et al.
Publicado: (2020)

CARM1 arginine methyltransferase as a therapeutic target for cancer
por: Santos, Margarida, et al.
Publicado: (2023)

Role of methyltransferase-like enzyme 3 and methyltransferase-like enzyme 14 in urological cancers
por: Tao, Zijia, et al.
Publicado: (2020)

Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers
por: Vinet, Mathilde, et al.
Publicado: (2019)

Mitochondrial Dynamics: A Potential Therapeutic Target for Ischemic Stroke
por: Zhou, Xiangyue, et al.
Publicado: (2021)

Biological functions of m(6)A methyltransferases
por: Gu, Jianzhong, et al.
Publicado: (2021)

The Role of Cellular Prion Protein in Cancer Biology: A Potential Therapeutic Target
por: Ding, Manqiu, et al.
Publicado: (2021)

Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target?
por: Yousaf, Saba, et al.
Publicado: (2022)

Comprehensive transcriptomic profiling and mutational landscape of primary gastric linitis plastica
por: Liu, Zhu, et al.
Publicado: (2022)

Correction: Comprehensive transcriptomic profiling and mutational landscape of primary gastric linitis plastica
por: Liu, Zhu, et al.
Publicado: (2023)

Succinylation modification: a potential therapeutic target in stroke
por: Lian, Jie, et al.
Publicado: (2023)

Protein arginine methyltransferases: promising targets for cancer therapy
por: Hwang, Jee Won, et al.
Publicado: (2021)

Coronavirus 2′-O-methyltransferase: A promising therapeutic target
por: Schindewolf, Craig, et al.
Publicado: (2023)

Autophagy in Gastric Mucosa: The Dual Role and Potential Therapeutic Target
por: Lu, Sheng-Yu, et al.
Publicado: (2021)

DIPG-14. PROTEOGENOMICS PROFILING REVEALS ENRICHED NON-HISTONE PROTEIN METHYLTRANSFERASES AS NEW THERAPEUTIC TARGETS IN DIPG
por: Anguraj Vadivel, Arun Kumaran, et al.
Publicado: (2023)

Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma
por: Nguyen, Hong Phuong, et al.
Publicado: (2023)

Bromodomain and extraterminal (BET) proteins: biological functions, diseases, and targeted therapy
por: Wang, Zhi-Qiang, et al.
Publicado: (2023)

Protein methyltransferase inhibitors as precision cancer therapeutics: a decade of discovery
por: Copeland, Robert A.
Publicado: (2018)

Molecular Targets in Alzheimer's Disease: From Pathogenesis to Therapeutics
por: Cheng, Xuan, et al.
Publicado: (2015)

Biological Functions and Therapeutic Potential of Autophagy in Spinal Cord Injury
por: Liao, Hai-Yang, et al.
Publicado: (2021)

A New Potential Therapeutic Target for Cancer in Ubiquitin-Like Proteins—UBL3
por: Zhang, Hengsen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_pkpm54nouv5miu8dmlid7mbedl