The role of peripheral β-amyloid in insulin resistance, insulin secretion, and prediabetes: in vitro and population-based studies

BACKGROUND: Previous experimental studies have shown that mice overexpressing amyloid precursor protein, in which β-amyloid (Aβ) is overproduced, exhibit peripheral insulin resistance, pancreatic impairment, and hyperglycemia. We aimed to explore the effects of Aβ on insulin action and insulin secre...

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Detalles Bibliográficos
Autores principales: Xu, Zihui, Chen, Juan, Wang, Pei, Li, Linyan, Hu, Shan, Liu, Hongjie, Huang, Yue, Mo, Xiaoxing, Yan, Hong, Shan, Zhilei, Wang, Di, Xu, Jian, Liu, Liegang, Peng, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394827/
https://www.ncbi.nlm.nih.gov/pubmed/37538787
http://dx.doi.org/10.3389/fendo.2023.1195658

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