ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC

BACKGROUND: The accumulation of reactive oxygen species (ROS) in tumor microenvironment (TME) is an important player for tumorigenesis and progression. We aimed to explore the outcomes of ROS on tumor vessels and the potential regulated mechanisms. METHODS: Exogenous H(2)O(2) was adopted to simulate...

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Detalles Bibliográficos
Autores principales: Zhao, Ye, Yu, Jing, Huang, Ai, Yang, Qin, Li, Guiling, Yang, Yong, Chen, Yeshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394868/
https://www.ncbi.nlm.nih.gov/pubmed/37528424
http://dx.doi.org/10.1186/s12935-023-03003-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394868/
https://www.ncbi.nlm.nih.gov/pubmed/37528424
http://dx.doi.org/10.1186/s12935-023-03003-8

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