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ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC
BACKGROUND: The accumulation of reactive oxygen species (ROS) in tumor microenvironment (TME) is an important player for tumorigenesis and progression. We aimed to explore the outcomes of ROS on tumor vessels and the potential regulated mechanisms. METHODS: Exogenous H(2)O(2) was adopted to simulate...
Autores principales: | Zhao, Ye, Yu, Jing, Huang, Ai, Yang, Qin, Li, Guiling, Yang, Yong, Chen, Yeshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394868/ https://www.ncbi.nlm.nih.gov/pubmed/37528424 http://dx.doi.org/10.1186/s12935-023-03003-8 |
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