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Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes

BACKGROUND: RNA profiling technologies at single-cell resolutions, including single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, scnRNA-seq for short), can help characterize the composition of tissues and reveal cells that influence key functions in both healthy and disease tissue...

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Detalles Bibliográficos
Autores principales: Cobos, Francisco Avila, Panah, Mohammad Javad Najaf, Epps, Jessica, Long, Xiaochen, Man, Tsz-Kwong, Chiu, Hua-Sheng, Chomsky, Elad, Kiner, Evgeny, Krueger, Michael J., di Bernardo, Diego, Voloch, Luis, Molenaar, Jan, van Hooff, Sander R., Westermann, Frank, Jansky, Selina, Redell, Michele L., Mestdagh, Pieter, Sumazin, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394903/
https://www.ncbi.nlm.nih.gov/pubmed/37528411
http://dx.doi.org/10.1186/s13059-023-03016-6