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Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life
OBJECTIVE: To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). METHODS: Quasi-experimental controlled trial. Thirty-six individuals...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394955/ https://www.ncbi.nlm.nih.gov/pubmed/36574616 http://dx.doi.org/10.1177/08919887221149152 |
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author | Borges-Machado, Flávia Teixeira, Laetitia Carvalho, Joana Ribeiro, Oscar |
author_facet | Borges-Machado, Flávia Teixeira, Laetitia Carvalho, Joana Ribeiro, Oscar |
author_sort | Borges-Machado, Flávia |
collection | PubMed |
description | OBJECTIVE: To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). METHODS: Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 ± 5.87 years) or a control group (aged 81.83 ± 6.18 years). The Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life – Alzheimer’s Disease (QoL-AD) tests were performed before and after the intervention. RESULTS: There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 – 5.28, P = .513), NPI (B = −8.35, 95% CI: −18.48 – 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 – 5.73, P = .058). CONCLUSIONS: The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. Future studies with larger samples are needed to better understand the impact of physical exercise interventions using MT methodology on specific cognitive abilities, neuropsychiatric symptoms, and quality of life domains. |
format | Online Article Text |
id | pubmed-10394955 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-103949552023-08-03 Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life Borges-Machado, Flávia Teixeira, Laetitia Carvalho, Joana Ribeiro, Oscar J Geriatr Psychiatry Neurol Original Articles OBJECTIVE: To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). METHODS: Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 ± 5.87 years) or a control group (aged 81.83 ± 6.18 years). The Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life – Alzheimer’s Disease (QoL-AD) tests were performed before and after the intervention. RESULTS: There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 – 5.28, P = .513), NPI (B = −8.35, 95% CI: −18.48 – 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 – 5.73, P = .058). CONCLUSIONS: The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. Future studies with larger samples are needed to better understand the impact of physical exercise interventions using MT methodology on specific cognitive abilities, neuropsychiatric symptoms, and quality of life domains. SAGE Publications 2022-12-27 2023-09 /pmc/articles/PMC10394955/ /pubmed/36574616 http://dx.doi.org/10.1177/08919887221149152 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Borges-Machado, Flávia Teixeira, Laetitia Carvalho, Joana Ribeiro, Oscar Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title | Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title_full | Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title_fullStr | Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title_full_unstemmed | Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title_short | Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life |
title_sort | does multicomponent physical exercise training work for dementia? exploring the effects on cognition, neuropsychiatric symptoms, and quality of life |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394955/ https://www.ncbi.nlm.nih.gov/pubmed/36574616 http://dx.doi.org/10.1177/08919887221149152 |
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