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RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma

Radiotherapy induces DNA damage, resulting in cell cycle arrest and activation of cell-intrinsic death pathways. However, the radioresistance of some tumour entities such as malignant melanoma limits its clinical application. The innate immune sensing receptor retinoic acid-inducible gene I (RIG-I)...

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Detalles Bibliográficos
Autores principales:	Lambing, Silke, Tan, Yu Pan, Vasileiadou, Paraskevi, Holdenrieder, Stefan, Müller, Patrick, Hagen, Christian, Garbe, Stephan, Behrendt, Rayk, Schlee, Martin, van den Boorn, Jasper G, Bartok, Eva, Renn, Marcel, Hartmann, Gunther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394996/ https://www.ncbi.nlm.nih.gov/pubmed/36626927 http://dx.doi.org/10.1093/jmcb/mjad001

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