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Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study

The aim of the present cross-sectional exploratory pilot study was to analyze the ability of the Phase Angle (PhA) to predict physical function, muscle strength and bone indicators, upon adjusting for potential confounders [age, sex, lean mass, and body mass index (BMI)]. This study included 56 phys...

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Autores principales: Duarte Martins, Alexandre, Paulo Brito, João, Batalha, Nuno, Oliveira, Rafael, Parraca, Jose A., Fernandes, Orlando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395046/
https://www.ncbi.nlm.nih.gov/pubmed/37539181
http://dx.doi.org/10.1016/j.heliyon.2023.e17593
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author Duarte Martins, Alexandre
Paulo Brito, João
Batalha, Nuno
Oliveira, Rafael
Parraca, Jose A.
Fernandes, Orlando
author_facet Duarte Martins, Alexandre
Paulo Brito, João
Batalha, Nuno
Oliveira, Rafael
Parraca, Jose A.
Fernandes, Orlando
author_sort Duarte Martins, Alexandre
collection PubMed
description The aim of the present cross-sectional exploratory pilot study was to analyze the ability of the Phase Angle (PhA) to predict physical function, muscle strength and bone indicators, upon adjusting for potential confounders [age, sex, lean mass, and body mass index (BMI)]. This study included 56 physically independent older adults (age, 68.29 ± 3.01 years; BMI, 28.09 ± 4.37 kg/m(2)). A multi-frequency segmental bioelectrical impedance analysis was used to measure PhA at 50 KHz. Additionally, physical function was assessed through four functional capacity tests [30-sec chair‐stand; seated medicine ball throw (SMBT); timed up & go; and 6-min walking test (6 MWT)], muscle strength through the handgrip test (dominant side) and maximal isokinetic strength of the dominant knee flexor and extensor. Moreover, bone indicators and body composition were assessed through the dual energy X-ray absorptiometry. PhA was significantly associated with SMBT (r = 0.375, effect size (ES) = moderate); 6 MWT (r = 0.396, ES = moderate); 30-sec chair‐stand (rho = 0.314, ES = moderate); knee extension (rho = 0.566, ES = large) and flexion (r = 0.459, ES = moderate); handgrip (rho = 0.432, ES = moderate); whole-body bone mineral content (BMC) (r = 0.316, ES = moderate); femoral neck BMC (r = 0.469, ES = moderate); and femoral neck bone mineral density (BMD) (rho = 0.433, ES = moderate). Additionally, the results of multiple regression analysis demonstrated that PhA is significantly associated with SMBT (p < 0.001; R(2) = 0.629), 6 MWT (p = 0.004; R(2) = 0.214), knee extension (p < 0.001; R(2) = 0.697), knee flexion (p < 0.001; R(2) = 0.355), handgrip test (p < 0.001; R(2) = 0.774), whole-body BMC (p < 0.001; R(2) = 0.524), femoral neck BMC (p = 0.001; R(2) = 0.249), and femoral neck BMD (p = 0.020; R(2) = 0.153). The results of the preliminary analysis suggested that PhA is linked to muscle strength and some factors related to physical function and bone quality in community-dwelling older adults.
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spelling pubmed-103950462023-08-03 Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study Duarte Martins, Alexandre Paulo Brito, João Batalha, Nuno Oliveira, Rafael Parraca, Jose A. Fernandes, Orlando Heliyon Research Article The aim of the present cross-sectional exploratory pilot study was to analyze the ability of the Phase Angle (PhA) to predict physical function, muscle strength and bone indicators, upon adjusting for potential confounders [age, sex, lean mass, and body mass index (BMI)]. This study included 56 physically independent older adults (age, 68.29 ± 3.01 years; BMI, 28.09 ± 4.37 kg/m(2)). A multi-frequency segmental bioelectrical impedance analysis was used to measure PhA at 50 KHz. Additionally, physical function was assessed through four functional capacity tests [30-sec chair‐stand; seated medicine ball throw (SMBT); timed up & go; and 6-min walking test (6 MWT)], muscle strength through the handgrip test (dominant side) and maximal isokinetic strength of the dominant knee flexor and extensor. Moreover, bone indicators and body composition were assessed through the dual energy X-ray absorptiometry. PhA was significantly associated with SMBT (r = 0.375, effect size (ES) = moderate); 6 MWT (r = 0.396, ES = moderate); 30-sec chair‐stand (rho = 0.314, ES = moderate); knee extension (rho = 0.566, ES = large) and flexion (r = 0.459, ES = moderate); handgrip (rho = 0.432, ES = moderate); whole-body bone mineral content (BMC) (r = 0.316, ES = moderate); femoral neck BMC (r = 0.469, ES = moderate); and femoral neck bone mineral density (BMD) (rho = 0.433, ES = moderate). Additionally, the results of multiple regression analysis demonstrated that PhA is significantly associated with SMBT (p < 0.001; R(2) = 0.629), 6 MWT (p = 0.004; R(2) = 0.214), knee extension (p < 0.001; R(2) = 0.697), knee flexion (p < 0.001; R(2) = 0.355), handgrip test (p < 0.001; R(2) = 0.774), whole-body BMC (p < 0.001; R(2) = 0.524), femoral neck BMC (p = 0.001; R(2) = 0.249), and femoral neck BMD (p = 0.020; R(2) = 0.153). The results of the preliminary analysis suggested that PhA is linked to muscle strength and some factors related to physical function and bone quality in community-dwelling older adults. Elsevier 2023-06-23 /pmc/articles/PMC10395046/ /pubmed/37539181 http://dx.doi.org/10.1016/j.heliyon.2023.e17593 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Duarte Martins, Alexandre
Paulo Brito, João
Batalha, Nuno
Oliveira, Rafael
Parraca, Jose A.
Fernandes, Orlando
Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title_full Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title_fullStr Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title_full_unstemmed Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title_short Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
title_sort phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: a cross-sectional exploratory pilot study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395046/
https://www.ncbi.nlm.nih.gov/pubmed/37539181
http://dx.doi.org/10.1016/j.heliyon.2023.e17593
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