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Dose- and application route-dependent effects of betahistine on behavioral recovery and neuroplasticity after acute unilateral labyrinthectomy in rats

INTRODUCTION: Betahistine is widely used for the treatment of various vestibular disorders. However, the approved oral administration route and maximum daily dose are evidently not effective in clinical trials, possibly due to a major first-pass metabolism by monoamine oxidases (MAOs). The current s...

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Detalles Bibliográficos
Autores principales:	Antons, Melissa, Lindner, Magdalena, Eilles, Eva, Günther, Lisa, Delker, Astrid, Branner, Christina, Krämer, Anja, Beck, Roswitha, Oos, Rosel, Wuehr, Max, Ziegler, Sibylle, Strupp, Michael, Zwergal, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395078/ https://www.ncbi.nlm.nih.gov/pubmed/37538257 http://dx.doi.org/10.3389/fneur.2023.1175481

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