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Setting the optimal positive end-expiratory pressure: a narrative review

The primary goals of positive end-expiratory pressure (PEEP) are to restore functional residual capacity through recruitment and prevention of alveolar collapse. Through these mechanisms, PEEP improves arterial oxygenation and may reduce the risk of ventilator-induced lung injury (VILI). Because of...

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Autor principal: Zersen, Kristin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395088/
https://www.ncbi.nlm.nih.gov/pubmed/37538169
http://dx.doi.org/10.3389/fvets.2023.1083290
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author Zersen, Kristin M.
author_facet Zersen, Kristin M.
author_sort Zersen, Kristin M.
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description The primary goals of positive end-expiratory pressure (PEEP) are to restore functional residual capacity through recruitment and prevention of alveolar collapse. Through these mechanisms, PEEP improves arterial oxygenation and may reduce the risk of ventilator-induced lung injury (VILI). Because of the many potential negative effects associated with the use of PEEP, much research has concentrated on determining the optimal PEEP setting. Arterial oxygenation targets and pressure-volume loops have been utilized to set the optimal PEEP for decades. Several other techniques have been suggested, including the use of PEEP tables, compliance, driving pressure (DP), stress index (SI), transpulmonary pressures, imaging, and electrical impedance tomography. Each of these techniques has its own benefits and limitations and there is currently not one technique that is recommended above all others.
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spelling pubmed-103950882023-08-03 Setting the optimal positive end-expiratory pressure: a narrative review Zersen, Kristin M. Front Vet Sci Veterinary Science The primary goals of positive end-expiratory pressure (PEEP) are to restore functional residual capacity through recruitment and prevention of alveolar collapse. Through these mechanisms, PEEP improves arterial oxygenation and may reduce the risk of ventilator-induced lung injury (VILI). Because of the many potential negative effects associated with the use of PEEP, much research has concentrated on determining the optimal PEEP setting. Arterial oxygenation targets and pressure-volume loops have been utilized to set the optimal PEEP for decades. Several other techniques have been suggested, including the use of PEEP tables, compliance, driving pressure (DP), stress index (SI), transpulmonary pressures, imaging, and electrical impedance tomography. Each of these techniques has its own benefits and limitations and there is currently not one technique that is recommended above all others. Frontiers Media S.A. 2023-07-19 /pmc/articles/PMC10395088/ /pubmed/37538169 http://dx.doi.org/10.3389/fvets.2023.1083290 Text en Copyright © 2023 Zersen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Zersen, Kristin M.
Setting the optimal positive end-expiratory pressure: a narrative review
title Setting the optimal positive end-expiratory pressure: a narrative review
title_full Setting the optimal positive end-expiratory pressure: a narrative review
title_fullStr Setting the optimal positive end-expiratory pressure: a narrative review
title_full_unstemmed Setting the optimal positive end-expiratory pressure: a narrative review
title_short Setting the optimal positive end-expiratory pressure: a narrative review
title_sort setting the optimal positive end-expiratory pressure: a narrative review
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395088/
https://www.ncbi.nlm.nih.gov/pubmed/37538169
http://dx.doi.org/10.3389/fvets.2023.1083290
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