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Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly utilized to reduce pain, inflammation, and fever. This study aimed to assess patterns of use and awareness of NSAID-related side-effects in an adult Jordanian. And the associations with sociodemographic factors. Methods: This cr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395194/ https://www.ncbi.nlm.nih.gov/pubmed/37527416 http://dx.doi.org/10.1080/07853890.2023.2242248 |
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author | Farah, Randa I. Khatib, Aseil E. Abu Ziyad, Hiba J. Jiad, Dareen K. Al Qusous, Lara R. Ababneh, Ali Jamal Ajarmeh, Salma |
author_facet | Farah, Randa I. Khatib, Aseil E. Abu Ziyad, Hiba J. Jiad, Dareen K. Al Qusous, Lara R. Ababneh, Ali Jamal Ajarmeh, Salma |
author_sort | Farah, Randa I. |
collection | PubMed |
description | Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly utilized to reduce pain, inflammation, and fever. This study aimed to assess patterns of use and awareness of NSAID-related side-effects in an adult Jordanian. And the associations with sociodemographic factors. Methods: This cross-sectional study among a representative sample of 604 adults >18 years. A validated, self-administered questionnaire was used to collect basic sociodemographic data from the participants, as well as information regarding NSAID use. Results: Most respondents were NSAID users (65.7%), female (53.4%) and under 50 years of age (74.5%). Overall, 42.6% had been prescribed NSAIDs by a physician. Male gender and smoking were negatively correlated with NSAIDs use (multivariable odds ratio [OR]: 0.5, 95% confidence interval [CI]: 0.4–0.8, p = 0.001 and OR: 0.6, 95% CI 0.4–0.8, p = 0.003). In contrast, the Ministry of Health Insurance was associated with NSAIDs use with OR: 1.6, 95% CI: 1.1–2.6, p = 0.03. Overall, 65.1% were aware of kidney NSAID-related side-effects and 22.4% were aware of the increased risk of asthma and allergy. Conclusion: Despite the high frequency of NSAID use in the Jordanian general population, there is limited knowledge of their side-effects as well as drug interactions. This is cause for concern, particularly as many participants reported having been prescribed NSAIDs by physicians without adequate patient safety education. |
format | Online Article Text |
id | pubmed-10395194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-103951942023-08-03 Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population Farah, Randa I. Khatib, Aseil E. Abu Ziyad, Hiba J. Jiad, Dareen K. Al Qusous, Lara R. Ababneh, Ali Jamal Ajarmeh, Salma Ann Med Research Article Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly utilized to reduce pain, inflammation, and fever. This study aimed to assess patterns of use and awareness of NSAID-related side-effects in an adult Jordanian. And the associations with sociodemographic factors. Methods: This cross-sectional study among a representative sample of 604 adults >18 years. A validated, self-administered questionnaire was used to collect basic sociodemographic data from the participants, as well as information regarding NSAID use. Results: Most respondents were NSAID users (65.7%), female (53.4%) and under 50 years of age (74.5%). Overall, 42.6% had been prescribed NSAIDs by a physician. Male gender and smoking were negatively correlated with NSAIDs use (multivariable odds ratio [OR]: 0.5, 95% confidence interval [CI]: 0.4–0.8, p = 0.001 and OR: 0.6, 95% CI 0.4–0.8, p = 0.003). In contrast, the Ministry of Health Insurance was associated with NSAIDs use with OR: 1.6, 95% CI: 1.1–2.6, p = 0.03. Overall, 65.1% were aware of kidney NSAID-related side-effects and 22.4% were aware of the increased risk of asthma and allergy. Conclusion: Despite the high frequency of NSAID use in the Jordanian general population, there is limited knowledge of their side-effects as well as drug interactions. This is cause for concern, particularly as many participants reported having been prescribed NSAIDs by physicians without adequate patient safety education. Taylor & Francis 2023-08-01 /pmc/articles/PMC10395194/ /pubmed/37527416 http://dx.doi.org/10.1080/07853890.2023.2242248 Text en © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. |
spellingShingle | Research Article Farah, Randa I. Khatib, Aseil E. Abu Ziyad, Hiba J. Jiad, Dareen K. Al Qusous, Lara R. Ababneh, Ali Jamal Ajarmeh, Salma Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title | Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title_full | Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title_fullStr | Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title_full_unstemmed | Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title_short | Pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the Jordanian population |
title_sort | pattern of use and awareness of side-effects of non-steroidal anti-inflammatory drugs in the jordanian population |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395194/ https://www.ncbi.nlm.nih.gov/pubmed/37527416 http://dx.doi.org/10.1080/07853890.2023.2242248 |
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