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Cilengitide inhibits osteoclast adhesion through blocking the α(v)β(3)-mediated FAK/Src signaling pathway

The remodeling of actin cytoskeleton of osteoclasts on the bone matrix is essential for osteoclastic resorption activity. A specific regulator of the osteoclast cytoskeleton, integrin α(v)β(3), is known to provide a key role in the degradation of mineralized bone matrixes. Cilengitide is a potent in...

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Detalles Bibliográficos
Autores principales:	Guo, Dan-yang, Chen, Zhong-hua, Fu, Yi-fei, Li, Yue-yue, Chen, Meng-nan, Wu, Jun-jie, Yuan, Zheng-dong, Ye, Jun-Xing, Li, Xia, Yuan, Feng-lai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395300/ https://www.ncbi.nlm.nih.gov/pubmed/37539209 http://dx.doi.org/10.1016/j.heliyon.2023.e17841

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