Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression

The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and pancreatic cancer. Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia, and as such plays a critical role in driving cancer progression. Us...

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Detalles Bibliográficos
Autores principales: Rafaeva, Maria, Jensen, Adina R. D., Horton, Edward R., Zornhagen, Kamilla W., Strøbech, Jan E., Fleischhauer, Lutz, Mayorca-Guiliani, Alejandro E., Nielsen, Sebastian R., Grønseth, Dina S., Kuś, Filip, Schoof, Erwin M., Arnes, Luis, Koch, Manuel, Clausen-Schaumann, Hauke, Izzi, Valerio, Reuten, Raphael, Erler, Janine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395327/
https://www.ncbi.nlm.nih.gov/pubmed/37539058
http://dx.doi.org/10.3389/fimmu.2023.1154528

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