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Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats

Leucine-rich glioma-inactivated 1 (LGI1) was identified as a causative gene of autosomal dominant lateral temporal lobe epilepsy. We previously reported that Lgi1-mutant rats carrying a missense mutation (L385R) showed audiogenic seizure-susceptibility. To explore the pathophysiological mechanisms u...

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Detalles Bibliográficos
Autores principales:	Kinboshi, Masato, Shimizu, Saki, Tokudome, Kentaro, Mashimo, Tomoji, Serikawa, Tadao, Ito, Hidefumi, Takahashi, Ryosuke, Ikeda, Akio, Ohno, Yukihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395352/ https://www.ncbi.nlm.nih.gov/pubmed/37539249 http://dx.doi.org/10.1016/j.heliyon.2023.e17984

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