Loss of Flot2 expression in deep cerebellar nuclei neurons of mice with Niemann-Pick disease type C

Niemann-Pick disease type C (NPC) is caused by a deficiency of the NPC1 or NPC2 gene, leading to storages of unesterified cholesterol and sphingolipids. Cerebellar ataxia is a main symptom of NPC and the deep cerebellar nuclei (DCN) is the sole signal output of the cerebellum. In this study, we expl...

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Detalles Bibliográficos
Autores principales: Chen, Tsu-I, Hsu, Pei-Chun, Lee, Ni-Chung, Liu, Yu-Han, Wang, Hao-Chun, Lu, Yen-Hsu, Chien, Yin-Hsiu, Hwu, Wuh-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395362/
https://www.ncbi.nlm.nih.gov/pubmed/37539272
http://dx.doi.org/10.1016/j.heliyon.2023.e18082

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