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P30 A longitudinal perspective of antimicrobial resistance evolution within urinary tract infection-based clinical trials

BACKGROUND: The mainstay treatments for urinary tract infections (UTIs) are nitrofurantoin and trimethoprim. The common route to acquire trimethoprim resistance (TriR) is via horizontal transfer of the trimethoprim-insensitive dihydrofolate reductase: dfrA. In contrast, nitrofurantoin resistance (Ni...

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Detalles Bibliográficos
Autores principales: Aldridge, Phillip, Tan, Aaron, Spencer, Alexandra, Vallée, Maxime, Harding, Chris, Hall, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395445/
http://dx.doi.org/10.1093/jacamr/dlad077.034