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Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection

OBJECTIVES: Acute type A aortic dissection (ATAAD) with severe stenosis or occlusion of the true lumen of aortic arch branch vessels often leads to an increased incidence of severe postsurgical neurological complications and mortality rate. In this study, we aimed to introduce our institutional extr...

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Autores principales: Sun, Jingwei, Xue, Chao, Zhang, Jinglong, Yang, Chen, Ren, Kai, Zhu, Hanzhao, Zhang, Bin, Li, Xiayun, Zhao, Hongliang, Jin, Zhenxiao, Liu, Jincheng, Duan, Weixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395476/
https://www.ncbi.nlm.nih.gov/pubmed/37539273
http://dx.doi.org/10.1016/j.heliyon.2023.e18251
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author Sun, Jingwei
Xue, Chao
Zhang, Jinglong
Yang, Chen
Ren, Kai
Zhu, Hanzhao
Zhang, Bin
Li, Xiayun
Zhao, Hongliang
Jin, Zhenxiao
Liu, Jincheng
Duan, Weixun
author_facet Sun, Jingwei
Xue, Chao
Zhang, Jinglong
Yang, Chen
Ren, Kai
Zhu, Hanzhao
Zhang, Bin
Li, Xiayun
Zhao, Hongliang
Jin, Zhenxiao
Liu, Jincheng
Duan, Weixun
author_sort Sun, Jingwei
collection PubMed
description OBJECTIVES: Acute type A aortic dissection (ATAAD) with severe stenosis or occlusion of the true lumen of aortic arch branch vessels often leads to an increased incidence of severe postsurgical neurological complications and mortality rate. In this study, we aimed to introduce our institutional extra-anatomic revascularization and cannulation strategy with improved postoperative outcomes for better management of patients with cerebral malperfusion in the setting of ATAAD. METHODS: Twenty-eight patients with ATAAD complicated by severe stenosis or occlusion of the aortic arch branch vessels, as noted on combined computed tomography angiography of the aorta and craniocervical artery, between January 2021 and June 2022 were included in this study. Basic patient characteristics, surgical procedures, hospitalization stays, and early follow-up results were analyzed. RESULTS: The median follow-up duration was 16.5 months (interquartile range: 11.5–20.5), with a 100% completion rate. The 30-day mortality rates was 7.1% (2/28 patients); two patients had multiple cerebral infarctions on preoperative computed tomography and persistent coma. Postoperative transient neurological dysfunction occurred in 10.7% (3/28) of the patients, and no new permanent neurological dysfunction occurred. Of all the patients, 3.6% (1/28) had novel acute renal failure. No other deaths, secondary surgeries, or serious complications occurred during the early follow-up period. CONCLUSIONS: Use of extra-anatomic revascularization and a new cannulation strategy before cardiopulmonary bypass is safe and feasible and may reduce the high incidence of postoperative neurological complications in patients with ATAAD and cerebral malperfusion.
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spelling pubmed-103954762023-08-03 Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection Sun, Jingwei Xue, Chao Zhang, Jinglong Yang, Chen Ren, Kai Zhu, Hanzhao Zhang, Bin Li, Xiayun Zhao, Hongliang Jin, Zhenxiao Liu, Jincheng Duan, Weixun Heliyon Research Article OBJECTIVES: Acute type A aortic dissection (ATAAD) with severe stenosis or occlusion of the true lumen of aortic arch branch vessels often leads to an increased incidence of severe postsurgical neurological complications and mortality rate. In this study, we aimed to introduce our institutional extra-anatomic revascularization and cannulation strategy with improved postoperative outcomes for better management of patients with cerebral malperfusion in the setting of ATAAD. METHODS: Twenty-eight patients with ATAAD complicated by severe stenosis or occlusion of the aortic arch branch vessels, as noted on combined computed tomography angiography of the aorta and craniocervical artery, between January 2021 and June 2022 were included in this study. Basic patient characteristics, surgical procedures, hospitalization stays, and early follow-up results were analyzed. RESULTS: The median follow-up duration was 16.5 months (interquartile range: 11.5–20.5), with a 100% completion rate. The 30-day mortality rates was 7.1% (2/28 patients); two patients had multiple cerebral infarctions on preoperative computed tomography and persistent coma. Postoperative transient neurological dysfunction occurred in 10.7% (3/28) of the patients, and no new permanent neurological dysfunction occurred. Of all the patients, 3.6% (1/28) had novel acute renal failure. No other deaths, secondary surgeries, or serious complications occurred during the early follow-up period. CONCLUSIONS: Use of extra-anatomic revascularization and a new cannulation strategy before cardiopulmonary bypass is safe and feasible and may reduce the high incidence of postoperative neurological complications in patients with ATAAD and cerebral malperfusion. Elsevier 2023-07-15 /pmc/articles/PMC10395476/ /pubmed/37539273 http://dx.doi.org/10.1016/j.heliyon.2023.e18251 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Sun, Jingwei
Xue, Chao
Zhang, Jinglong
Yang, Chen
Ren, Kai
Zhu, Hanzhao
Zhang, Bin
Li, Xiayun
Zhao, Hongliang
Jin, Zhenxiao
Liu, Jincheng
Duan, Weixun
Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title_full Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title_fullStr Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title_full_unstemmed Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title_short Extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type A aortic dissection
title_sort extra-anatomic revascularization and a new cannulation strategy for preoperative cerebral malperfusion due to severe stenosis or occlusion of supra-aortic branch vessels in acute type a aortic dissection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395476/
https://www.ncbi.nlm.nih.gov/pubmed/37539273
http://dx.doi.org/10.1016/j.heliyon.2023.e18251
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