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Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study

INTRODUCTION: Metabolic syndrome, a constellation of features such as obesity, hypertension, dyslipidemia and insulin resistance is of common occurrence in patients with psoriasis. Systemic inflammation is supposed to play a significant role in both conditions. The co-occurrence of metabolic syndrom...

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Autores principales: Thapa, Pratichya, Paudel, Sangeeta, Uprety, Shraddha, Timalsina, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395577/
http://dx.doi.org/10.31729/jnma.8225
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author Thapa, Pratichya
Paudel, Sangeeta
Uprety, Shraddha
Timalsina, Santosh
author_facet Thapa, Pratichya
Paudel, Sangeeta
Uprety, Shraddha
Timalsina, Santosh
author_sort Thapa, Pratichya
collection PubMed
description INTRODUCTION: Metabolic syndrome, a constellation of features such as obesity, hypertension, dyslipidemia and insulin resistance is of common occurrence in patients with psoriasis. Systemic inflammation is supposed to play a significant role in both conditions. The co-occurrence of metabolic syndrome and psoriasis can result in clinical consequences. The aim of this study was to find out the prevalence of metabolic syndrome among patients with psoriasis attending the Outpatient Department of Dermatology, Venereology and Leprology in a tertiary care centre. METHOD: A descriptive cross-sectional study was conducted in the Outpatient Department of Dermatology, Venereology and Leprology from 4 July 2022 to 4 May 2023. The ethical approval was obtained from Institutional Review Committee (Reference number: CMC-IRC/078/079-300). Patients aged more than 18 years diagnosed with psoriasis who provided written consent were enrolled in the study. Pregnant female patients and those who did not give informed consent were excluded from the study. Convenience sampling method was used. Point estimate and 90% Confidence Interval were calculated. RESULTS: Among 72 patients with psoriasis, the prevalence of metabolic syndrome was 15 (20.83%) (12.98-28.68, 90% Confidence Interval). Obesity 13 (86.67%) and hypertriglyceridemia 13 (86.67%) were the frequent most individual components of metabolic syndrome. CONCLUSIONS: The prevalence of metabolic syndrome among psoriatic patients was lower than other studies done in similar settings.
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spelling pubmed-103955772023-08-03 Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study Thapa, Pratichya Paudel, Sangeeta Uprety, Shraddha Timalsina, Santosh JNMA J Nepal Med Assoc Original Article INTRODUCTION: Metabolic syndrome, a constellation of features such as obesity, hypertension, dyslipidemia and insulin resistance is of common occurrence in patients with psoriasis. Systemic inflammation is supposed to play a significant role in both conditions. The co-occurrence of metabolic syndrome and psoriasis can result in clinical consequences. The aim of this study was to find out the prevalence of metabolic syndrome among patients with psoriasis attending the Outpatient Department of Dermatology, Venereology and Leprology in a tertiary care centre. METHOD: A descriptive cross-sectional study was conducted in the Outpatient Department of Dermatology, Venereology and Leprology from 4 July 2022 to 4 May 2023. The ethical approval was obtained from Institutional Review Committee (Reference number: CMC-IRC/078/079-300). Patients aged more than 18 years diagnosed with psoriasis who provided written consent were enrolled in the study. Pregnant female patients and those who did not give informed consent were excluded from the study. Convenience sampling method was used. Point estimate and 90% Confidence Interval were calculated. RESULTS: Among 72 patients with psoriasis, the prevalence of metabolic syndrome was 15 (20.83%) (12.98-28.68, 90% Confidence Interval). Obesity 13 (86.67%) and hypertriglyceridemia 13 (86.67%) were the frequent most individual components of metabolic syndrome. CONCLUSIONS: The prevalence of metabolic syndrome among psoriatic patients was lower than other studies done in similar settings. Journal of the Nepal Medical Association 2023-06 2023-06-30 /pmc/articles/PMC10395577/ http://dx.doi.org/10.31729/jnma.8225 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Thapa, Pratichya
Paudel, Sangeeta
Uprety, Shraddha
Timalsina, Santosh
Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_fullStr Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full_unstemmed Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_short Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_sort metabolic syndrome among patients with psoriasis attending the outpatient department of dermatology, venereology and leprology in a tertiary care centre: a descriptive cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395577/
http://dx.doi.org/10.31729/jnma.8225
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