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Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura
BACKGROUND: Solid pseudopapillary neoplasm, or Frantz-Gruber tumor, is a diagnostic challenge for the surgical pathologist. It is classified by the WHO as a malignant epithelial tumor of the pancreas, its prevalence is low, it occurs in only 1 to 2% of all malignant tumors of the pancreas, it usuall...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Mexicano del Seguro Social
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395929/ https://www.ncbi.nlm.nih.gov/pubmed/37207324 |
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author | Baltazar-Ramos, Javier Iván Martínez-Reyes, Gabriela Pérez-Corro, Miguel Ángel Denis-Rodríguez, Edmundo Melo-Santiesteban, Guadalupe |
author_facet | Baltazar-Ramos, Javier Iván Martínez-Reyes, Gabriela Pérez-Corro, Miguel Ángel Denis-Rodríguez, Edmundo Melo-Santiesteban, Guadalupe |
author_sort | Baltazar-Ramos, Javier Iván |
collection | PubMed |
description | BACKGROUND: Solid pseudopapillary neoplasm, or Frantz-Gruber tumor, is a diagnostic challenge for the surgical pathologist. It is classified by the WHO as a malignant epithelial tumor of the pancreas, its prevalence is low, it occurs in only 1 to 2% of all malignant tumors of the pancreas, it usually affects mainly young women, its origin is still unclear, it is generally It presents as a solitary, encapsulated lesion, without invasion of peripancreatic tissues with rare cases of metastasis, which is why it is considered a low-grade malignant tumor by the WHO. The objective of this article is to present three clinical cases and to evaluate the epidemiology, clinical manifestations, morphology and immunohistochemical expression of the tumor in a review of the bibliography, as well as to compare it with the cases already reported on the subject. CLINICAL CASE: Three cases of Frantz tumor were diagnosed by the pathology department of a tertiary hospital are presented, which correspond to two women aged 17 and 34, as well as a 52-year-old man whose presentation by age and sex is rare. CONCLUSIONS: After the bibliographical review and the analysis of the cases presented, we verified the difficulty to make a correct diagnosis, since its presence is rare in the daily practice of the surgical pathologist. The morphological patterns of the solid pseudopapillary tumor are varied and can often be reminiscent of neuroendocrine tumors of the pancreas, whose presentation rate is higher. |
format | Online Article Text |
id | pubmed-10395929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Instituto Mexicano del Seguro Social |
record_format | MEDLINE/PubMed |
spelling | pubmed-103959292023-08-04 Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura Baltazar-Ramos, Javier Iván Martínez-Reyes, Gabriela Pérez-Corro, Miguel Ángel Denis-Rodríguez, Edmundo Melo-Santiesteban, Guadalupe Rev Med Inst Mex Seguro Soc Casos Clínicos BACKGROUND: Solid pseudopapillary neoplasm, or Frantz-Gruber tumor, is a diagnostic challenge for the surgical pathologist. It is classified by the WHO as a malignant epithelial tumor of the pancreas, its prevalence is low, it occurs in only 1 to 2% of all malignant tumors of the pancreas, it usually affects mainly young women, its origin is still unclear, it is generally It presents as a solitary, encapsulated lesion, without invasion of peripancreatic tissues with rare cases of metastasis, which is why it is considered a low-grade malignant tumor by the WHO. The objective of this article is to present three clinical cases and to evaluate the epidemiology, clinical manifestations, morphology and immunohistochemical expression of the tumor in a review of the bibliography, as well as to compare it with the cases already reported on the subject. CLINICAL CASE: Three cases of Frantz tumor were diagnosed by the pathology department of a tertiary hospital are presented, which correspond to two women aged 17 and 34, as well as a 52-year-old man whose presentation by age and sex is rare. CONCLUSIONS: After the bibliographical review and the analysis of the cases presented, we verified the difficulty to make a correct diagnosis, since its presence is rare in the daily practice of the surgical pathologist. The morphological patterns of the solid pseudopapillary tumor are varied and can often be reminiscent of neuroendocrine tumors of the pancreas, whose presentation rate is higher. Instituto Mexicano del Seguro Social 2023 /pmc/articles/PMC10395929/ /pubmed/37207324 Text en © 2023 Revista Medica del Instituto Mexicano del Seguro Social. https://creativecommons.org/licenses/by-nc-nd/4.0/Esta obra está bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional. |
spellingShingle | Casos Clínicos Baltazar-Ramos, Javier Iván Martínez-Reyes, Gabriela Pérez-Corro, Miguel Ángel Denis-Rodríguez, Edmundo Melo-Santiesteban, Guadalupe Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title | Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title_full | Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title_fullStr | Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title_full_unstemmed | Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title_short | Neoplasia sólida pseudopapilar. Reporte de tres casos y revisión de la literatura |
title_sort | neoplasia sólida pseudopapilar. reporte de tres casos y revisión de la literatura |
topic | Casos Clínicos |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395929/ https://www.ncbi.nlm.nih.gov/pubmed/37207324 |
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