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Índice leucoglucémico en pacientes con infarto miocárdico con elevación del ST

BACKGROUND: The myocardial infarction-associated (MI) mortality is not only due cardiovascular complications, but intrahospital non-cardiovascular complications (IHnCVCs). The leuko-glycemic index (LGI) has been used as a prognostic marker for the development of cardiovascular complications in MI. W...

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Detalles Bibliográficos
Autores principales: Reyes-Villarreal, Juan Carlos, Morales-Gutiérrez, Joel Eduardo, López-Zamora, Berenice, Reyes-Navarro, Geraldine Vanessa, Ordoñez-González, Irvin, Triana-González, Salma, Peralta-Amaro, Ana Lilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Mexicano del Seguro Social 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396030/
https://www.ncbi.nlm.nih.gov/pubmed/35758939
Descripción
Sumario:BACKGROUND: The myocardial infarction-associated (MI) mortality is not only due cardiovascular complications, but intrahospital non-cardiovascular complications (IHnCVCs). The leuko-glycemic index (LGI) has been used as a prognostic marker for the development of cardiovascular complications in MI. We focused this study on identifying the cut-off point of LGI for the IHnCVCs development in patients with ST-segment elevation myocardial infarction (STEMI). MATERIAL AND METHODS: In this single-center and cross-sectional design, we included patients with STEMI. The biochemical analysis included glucose and leucocytes; with them we calculated the LGI. Receiver operating characteristic curve, univariate and bivariate analysis, and multivariate analysis for IHnCVCs development were performed. A p<0.05 was considered statistically significant. RESULTS: We included 1294 patients, 79.8% were men and 20.2% women. The main comorbidities were hypertension, diabetes mellitus and dyslipidemia. Six hundred forty-four (49.8%) patients presented IHNCVCs. The LGI > 1200 (AUC 0.817) predict the IHNCVCs development in STEMI patients. The variables that increased the IHNCVCs development were LGI > 1200, creatinine > 0.91 mg/dL, diabetes mellitus and age > 65 years. Hospital acquired pneumonia and cardiovascular complications increase the risk of death among STEMI patients. CONCLUSIONS: A LGI > 1200 increased, just over nine times, the risk of IHnCVC development in STEMI patients.