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Metal-polyDNA nanoparticles reconstruct osteoporotic microenvironment for enhanced osteoporosis treatment

Current clinical approaches to osteoporosis primarily target osteoclast biology, overlooking the synergistic role of bone cells, immune cells, cytokines, and inorganic components in creating an abnormal osteoporotic microenvironment. Here, metal-polyDNA nanoparticles (Ca-polyCpG MDNs) composed of Ca...

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Detalles Bibliográficos
Autores principales:	Liu, Xueliang, Li, Fan, Dong, Ziliang, Gu, Chao, Mao, Dongsheng, Chen, Jingqi, Luo, Lei, Huang, Yuting, Xiao, Jie, Li, Zhanchun, Liu, Zhuang, Yang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396296/ https://www.ncbi.nlm.nih.gov/pubmed/37531423 http://dx.doi.org/10.1126/sciadv.adf3329

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