Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer

Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer cells. SIRT1 is an NAD(+)-dependent epigenetic modifier whose activity is classically associated with healthy aging and longevity, but its functi...

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Detalles Bibliográficos
Autores principales: García-Martínez, José Manuel, Chocarro-Calvo, Ana, Martínez-Useros, Javier, Fernández-Aceñero, María Jesús, Fiuza, M Carmen, Cáceres-Rentero, José, De la Vieja, Antonio, Barbáchano, Antonio, Muñoz, Alberto, Larriba, María Jesús, García Jiménez, Custodia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396337/
https://www.ncbi.nlm.nih.gov/pubmed/37530744
http://dx.doi.org/10.7554/eLife.86913

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