Cargando…

Control of telomere length in yeast by SUMOylated PCNA and the Elg1 PCNA unloader

Telomeres cap and protect the linear eukaryotic chromosomes. Telomere length is determined by an equilibrium between positive and negative regulators of telomerase activity. A systematic screen for yeast mutants that affect telomere length maintenance in the yeast Saccharomyces cerevisiae revealed t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Pragyan, Gazy, Inbal, Kupiec, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396338/ https://www.ncbi.nlm.nih.gov/pubmed/37530521 http://dx.doi.org/10.7554/eLife.86990

Ejemplares similares

The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast
por: Tamang, Sanjeeta, et al.
Publicado: (2019)

Effects of Defective Unloading and Recycling of PCNA Revealed by the Analysis of ELG1 Mutants
por: Itzkovich, Ziv, et al.
Publicado: (2023)

The Yeast PCNA Unloader Elg1 RFC-Like Complex Plays a Role in Eliciting the DNA Damage Checkpoint
por: Sau, Soumitra, et al.
Publicado: (2019)

A structure–function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
por: Shemesh, Keren, et al.
Publicado: (2017)

Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?
por: Kubota, Takashi, et al.
Publicado: (2013)

Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation
por: Kubota, Takashi, et al.
Publicado: (2015)

The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition
por: Huang, Fu, et al.
Publicado: (2016)

Access to PCNA by Srs2 and Elg1 Controls the Choice between Alternative Repair Pathways in Saccharomyces cerevisiae
por: Arbel, Matan, et al.
Publicado: (2020)

PCNA Loaders and Unloaders—One Ring That Rules Them All
por: Arbel, Matan, et al.
Publicado: (2021)

Telomere length regulation by Rif1 protein from Hansenula polymorpha
por: Malyavko, Alexander N, et al.
Publicado: (2022)

The role of Rif1 in telomere length regulation is separable from its role in origin firing
por: Shubin, Calla B, et al.
Publicado: (2020)

Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex
por: Paul Solomon Devakumar, Lovely Jael, et al.
Publicado: (2019)

Identification of PCNA-interacting protein motifs in human DNA polymerase δ
por: Khandagale, Prashant, et al.
Publicado: (2020)

Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase
por: Colin, Léonard, et al.
Publicado: (2023)

A Genetic Screen for High Copy Number Suppressors of the Synthetic Lethality Between elg1Δ and srs2Δ in Yeast
por: Gazy, Inbal, et al.
Publicado: (2013)

Dual control of NAD(+) synthesis by purine metabolites in yeast
por: Pinson, Benoît, et al.
Publicado: (2019)

Ubiquitination-dependent control of sexual differentiation in fission yeast
por: Simonetti, Fabrizio, et al.
Publicado: (2017)

Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces
por: Hu, Xichan, et al.
Publicado: (2016)

SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
por: Godneeva, Baira, et al.
Publicado: (2023)

Telomere repeats induce domains of H3K27 methylation in Neurospora
por: Jamieson, Kirsty, et al.
Publicado: (2018)

PCNA Retention on DNA into G2/M Phase Causes Genome Instability in Cells Lacking Elg1
por: Johnson, Catherine, et al.
Publicado: (2016)

Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
por: Povedano, Juan Manuel, et al.
Publicado: (2018)

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment
por: Criqui, Mélanie, et al.
Publicado: (2020)

HAT3-mediated acetylation of PCNA precedes PCNA monoubiquitination following exposure to UV radiation in Leishmania donovani
por: Kumar, Devanand, et al.
Publicado: (2015)

The genetic basis of aneuploidy tolerance in wild yeast
por: Hose, James, et al.
Publicado: (2020)

Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae
por: Rosas Bringas, Fernando Rodrigo, et al.
Publicado: (2022)

The transcriptional elongation rate regulates alternative polyadenylation in yeast
por: Geisberg, Joseph V, et al.
Publicado: (2020)

Effective dynamics of nucleosome configurations at the yeast PHO5 promoter
por: Wolff, Michael Roland, et al.
Publicado: (2021)

The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis
por: Ivanyi-Nagy, Roland, et al.
Publicado: (2018)

New histone supply regulates replication fork speed and PCNA unloading
por: Mejlvang, Jakob, et al.
Publicado: (2014)

MutSα maintains the mismatch repair capability by inhibiting PCNA unloading
por: Kawasoe, Yoshitaka, et al.
Publicado: (2016)

Dissociation rate compensation mechanism for budding yeast pioneer transcription factors
por: Donovan, Benjamin T, et al.
Publicado: (2019)

Cohesin-dependence of neuronal gene expression relates to chromatin loop length
por: Calderon, Lesly, et al.
Publicado: (2022)

Genome-wide base editor screen identifies regulators of protein abundance in yeast
por: Schubert, Olga T, et al.
Publicado: (2022)

The molecular basis of coupling between poly(A)-tail length and translational efficiency
por: Xiang, Kehui, et al.
Publicado: (2021)

The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast
por: Wong, Io Nam, et al.
Publicado: (2019)

Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
por: Turner, Rachael Emily, et al.
Publicado: (2021)

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq
por: Claussin, Clémence, et al.
Publicado: (2017)

Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA
por: Donczew, Rafal, et al.
Publicado: (2020)

Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution
por: Shah, Shanaya Shital, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9708v5h375qjssgdjud2b73a08