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FTSH PROTEASE 3 facilitates Complex I degradation through a direct interaction with the Complex I subunit PSST

Complex I (CI) (NADH dehydrogenase), the largest complex involved in mitochondrial oxidative phosphorylation, is composed of nuclear- and mitochondrial-encoded subunits. CI assembly occurs via the sequential addition of subdomains and modules. As CI is prone to oxidative damage, its subunits continu...

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Detalles Bibliográficos
Autores principales: Ghifari, Abi S, Ivanova, Aneta, Berkowitz, Oliver, Whelan, James, Murcha, Monika W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396367/
https://www.ncbi.nlm.nih.gov/pubmed/37177987
http://dx.doi.org/10.1093/plcell/koad128

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